Runes, masteries, skill order and items on this page mirror what is actually being played in Classic on patch 26.16, not a reconstruction of a 2013 patch.
Skill Leveling Order
Max order E → Q → WMax in the order E → Q → W, taking R at 6, 11 and 16.
Item Build
Live Classic, patch 26.16Data collected 2026-08-16Build path · Doran's Blade → Berserker's Greaves → Infinity Edge → Phantom Dancer → The Bloodthirster
Masteries
Open in simulator →21 points into Offense to push early damage share.
Base Stats
Lv1 · growth · Lv18Skills
Passive · Q · W · E · RTwitch's basic attacks infect the target, dealing true damage each second.

Twitch becomes invisible for a short duration, while invisible Twitch gains movement speed. When leaving invisibility twitch gains Attack Speed for a short duration.

Twitch hurls a cask of venom that explodes in an area, slowing targets and applying deadly venom to the target.

All nearby enemies secrete Twitch's toxic venoms from their bodies, dealing damage for each stack.

Twitch closes his eyes and fires his crossbow, rapidly spraying powerful piercing bolts ahead of him.
Champion Tips
Riot officialPlaying as
- Twitch's attack speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
- Expunge has a large range; apply as many stacks of Deadly Venom as possible before using it.
- You can catch up to an enemy out of attack range with Venom Cask.
Playing against
- Twitch is fragile. Work with teammates to focus on him when you're able to catch him out of invisibility.
- Spell Shields won't block the damage from Deadly Venom, but they will block the effects Twitch can trigger with it.
- If you suspect Twitch has left the lane, let your teammates know that Twitch is ''MIA.''
Frequently Asked
The quick answers, straight from this buildWhat runes for Twitch?
Marks Greater Mark of Armor Penetration 9, Seals Greater Seal of Armor 9, Glyphs Greater Glyph of Magic Resist 9, Quints Greater Quintessence of Attack Damage 3
What mastery setup for Twitch?
21/9/0 split. 21 points into Offense to push early damage share.
What is Twitch’s skill order?
Max in the order E → Q → W, taking R whenever available. Max in the order E → Q → W, taking R at 6, 11 and 16.
What is Twitch’s item build?
Start: Doran's Blade → Boots: Berserker's Greaves → Core: Infinity Edge · Phantom Dancer · The Bloodthirster
Who is Twitch weak against?
Leona
Lore
The city-state of Zaun is a twisted realm of science, mercantilism, and magic run amok. While the young science of techmaturgy does much to advance civilization, its research and use in Zaun pushes the boundaries of morality on a daily basis. Zaun, ...





